Clinical bottom line
INTRAVENOUS IMMUNOGLOBULIN (IVIG) is a relatively safe and effective means of reducing the need for exchange transfusion in haemolytic disease of the newborn (Grade A)
The American Academy of Pediatrics 2004 guidelines recommend administration of IVIG in isoimmune haemolytic disease if the total serum bilirubin TSB is rising despite intensive phototherapy or the TSB level is within 2-3 mg/dl of the exchange level.
Source : Arch Dis Child September 2009 Vol 94 No 9 page 739
INTRAVENOUS IMMUNOGLOBULIN (IVIG) is a relatively safe and effective means of reducing the need for exchange transfusion in haemolytic disease of the newborn (Grade A)
The American Academy of Pediatrics 2004 guidelines recommend administration of IVIG in isoimmune haemolytic disease if the total serum bilirubin TSB is rising despite intensive phototherapy or the TSB level is within 2-3 mg/dl of the exchange level.
Source : Arch Dis Child September 2009 Vol 94 No 9 page 739
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